When Katsuhiko Hayashi and his colleagues announced in March that they had produced mouse pups from the cells of two male parents, the news literally floored some researchers.
Hayashi and his colleagues took cells from the tails of male mice, which have both X and Y sex chromosomes, and converted them into stem cells. In the process, roughly 3% of such cells spontaneously lose their Y chromosomes. The team then isolated these Y-less cells and treated them with a chemical that causes errors during cell division.
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